Sunday, April 01, 2012

Functional enhancers at the gene-poor 8q24 cancer-linked locus


Functional enhancers at the gene-poor 8q24 cancer-linked locus.

PLoS genetics, Vol. 5, No. 8. (14 August 2009), e1000597, doi:10.1371/journal.pgen.1000597
This paper is recommended by Diane Robins (University of Michigan), who writes that this paper

"is the first functional analysis of a SNP in a gene desert that proves to be a variation in a FOX binding site making it a better androgen-responsive long-range enhancer for myc.  Follow-up paper shows interaction over 500 kb.."

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