Saturday, March 24, 2012

SCNM1, a putative RNA splicing factor that modifies disease severity in mice

I use this paper in my graduate genetics course.  It describes the use of inbred strains to map and molecularly identify genes and illustrates a case of strain-specific phenotypes and genetic interactions.  It simultaneously illustrates the power of working with inbred strains and the caveat that phentypes can be strain-specific.

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