Functions of the nonsense-mediated mRNA decay pathway in Drosophila development.

Functions of the nonsense-mediated mRNA decay pathway in Drosophila development.

PLoS genetics, Vol. 2, No. 12. (29 December 2006), doi:10.1371/journal.pgen.0020180

by Mark M. Metzstein, Mark A. Krasnow

I use this this paper in my graduate genetics course to illustrate techniques for analysis of gene expression in Drosophila.  It's also a very nice example of serendipity, whereby mutations in a set of genes for a fundamental process (nonsense-mediated decay) were discovered while looking for something else entirely.